Cover the core emotions first
Start with happy, sad, angry, shocked, confused, laughing, thinking, please, thanks, and no. These reactions fit many different conversations.
Make each reaction visually distinct
If several stickers look too similar, users will only remember one of them. Change face shape, hand gesture, caption, or pose to make each mood easy to pick.
Use captions as labels, not paragraphs
Captions like nope, wait, really, oops, slay, and LMAO work because they are short enough to read at sticker size.